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Indomethacin (Indocin) is a prescription drug used to treat moderate to severe pain, swelling, and stiffness from arthritis.
Indomethacin belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs).
These drugs treat swelling, pain, and fever by blocking the production of substances in the body called prostaglandins, which regulate inflammation and other bodily processes.
Indomethacin is approved to treat: Moderate to severe osteoarthritis (wear-and-tear arthritis) Rheumatoid arthritis (inflammatory arthritis) Ankylosing spondylitis (inflammatory arthritis of the spine) Doctors may also use indomethacin to treat bursitis (shoulder joint inflammation), gout, or gouty arthritis, (a form of arthritis caused by crystals of uric acid building up inside joints), and inflammation of tendons (tissue that attaches muscles to bones).
The Food and Drug administration (FDA) approved indomethacin in 1965 for the drug company Iceutica Operations under the brand name Indocin.
Today, several drug manufacturers make generic versions of the drug.
It’s also sold under other brand names, including Indo-Lemmon and Tivorbex.
We have mentioned how a positive response to indomethacin is part of the Intravenous aspirin can be a useful drug to help withdrawal from medication A number of surgical treatments are available for cluster headache. A 42-year-old man, with no previous or family history of headache, developed He would typically also feel hot and clammy, agitated, and sometimes breathless.
Particularly relevant NSAIDs include ibuprofen, diclofenac, diflunisal, etodolac, fenoprofen, flurbiprofen, indomethacin, ketoprofen, ketorolac, mefenamic acid, meclofenamate, nabumetone, naproxen, oxaprozin or piroxicam.The pharmaceutical compositions can be administered intravenously, intrathecally, orally, via controlled release implant or pump, parenterally, sublingually, rectally, topically, via inhalation, etc. By using lower amounts of either or both drugs, the side effects associated with effective pain management in humans and other species are significantly reduced. Indomethacin damage to rat gastric mucosa is markedly dependent on luminal pH. The treatment of primary cough headaches include drugs that are known to reduce intracranial pressure: Acetazolamide Indomethacin Topiramate Other drugs have been used successfully in the past, again on a case by case basis without proper randomised trials: Methysergide (an anti-migraine drug) Naproxen Ergonovine IV Dihydroergotamine A Lumbar Puncture Procedure has also helped some patients.
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