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Lanoxin, sold under the brand name Lanoxin, is a prescription drug used to help treat arrhythmia (irregular heartbeat) and improve symptoms of fatigue caused by heart failure.
Lanoxin belongs to a group of drugs known as anti-arrhythmics, which work by preventing sodium from being pumped out of heart cells.
Lanoxin Warnings You should not take digoxin if you: Are allergic to digoxin or any of the ingredients in the medication Have an irregular heartbeat caused by ventricular fibrillation Talk to your doctor before taking digoxin if you: Have any current or previous heart conditions, including heart attack, endocarditis (infections of the heart muscle or in the lining that surrounds the heart), heart failure, or very slow heartbeat Have low concentrations of oxygen in the body, a condition known as hypoxia Have low levels of potassium or calcium in the blood, which might reduce the effect of digoxin High levels of calcium or low levels of magnesium in the blood Have Beriberi heart disease Have thyroid disease The concentration of digoxin in your blood can vary based on many factors and could become dangerous if not kept within a certain range.
Your doctor will probably have you come in for lab work from time to time to monitor your digoxin levels.
Lanoxin Use in the Elderly Lanoxin is considered safe to use in the elderly as long as the dose is no greater than 0.125 milligram (mg) or 125 mcg per day.
As we age, our kidney function changes and normally slows, so our bodies can’t get rid of certain substances, like digoxin, as quickly as they once could have.
Lanoxin overdose symptoms in elderly are sometimes hard to pinpoint without running laboratory tests.
Elderly people taking higher doses of digoxin may become delirious or confused and feel weak or tired.
Pregnancy and Lanoxin Lanoxin should only be taken by pregnant women when the risks outweigh the benefit.
Talk to your doctor if you are pregnant or might become pregnant before taking this medication.
Lanoxin has been found to pass into breast milk, so talk to your doctor if you are breastfeeding or plan to breastfeed.
BasicDescription Back to Top Lanoxin Side Effects Common Side Effects of Lanoxin You should tell your doctor if any of the following side effects become severe or don’t go away: Dizziness Changes in mood and mental alertness, including confusion, depression and lost interest in usual activities Anxiety Nausea, vomiting and diarrhea Headache Rash Growth or enlargement of breast tissue in men (gynecomastia) Weakness Serious Side Effects of Lanoxin You should call your doctor immediately if you experience any of the following serious side effects: Changes in heart rhythm, including irregular heartbeat Fast or racing heartbeat Heart stopping or flat-lining (asystole) Problems with electrical functioning of the heart known as heart block Visual problems, including blurry vision and yellow halos Low platelet count Back to Top Lanoxin Interactions Lanoxin interacts with many drugs.
As always, share with your doctor and pharmacist all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you’re taking.
You should not take Lanoxin if you are taking any herbal supplements belonging to the squill family, such as white quill or Mediterranean squill.
Before taking digoxin, tell your doctor if you are taking any of the following medications: Drugs for irregular heartbeat like: Pacerone, Nexterone, or Cordarone ( amiodarone ), Betapace or Betapace AF ( sotalol ), Tikosyn (dofetilde), Multaq (dronedarone), procainamide, or flecainide Aspirin (both tablet and suppository forms) Beta blockers like Zebeta or Ziac ( betaxolol ),Toprol XL or Lopressor ( metoprolol ), Tenormin ( atenolol ), and Bystolic ( nebivolol ) Heartburn medications like Prilosec ( omeprazole ), Nexium ( esomeprazole ), Aciphex ( rabeprazole ), Protonix ( pantoprazole ), and Dexilant (deslansoprazole) Other heartburn medications like Pepcid ( famotidine ) and Tums ( calcium carbonate ) The herbal supplement Lily of the Valley Macrolide antibiotics like Ery-Tab ( erythromycin ) and Biaxin ( clarithromycin ) Neoral, Sandimmune, and Gengraf ( cyclosporine ) Lanoxin and Alcohol Lanoxin can cause sleepiness, confusion, and problems with balance; drinking while taking digoxin could worsen these side effects.
For best results, avoid drinking alcohol while taking digoxin.
Slow ventricular responses may be caused by drugs that slow conduction through the AV node, such as digoxin, and in individuals with AV nodal disease.
An important goal of treatment in such patients is to avoid the use of medications that can potentially worsen the acute delirious state. -Diuretics, ACE inhibitors, spironolactone, beta-blockers, and digoxin are all a part of standard therapy for patients with heart failure or cardiomyopathy due to any cause. Table 111-4-2. Properties of Lanoxin Half-life (h) Clearance (mL1min) Protein binding (%) 1 I 1 20-40 130 (renal) 25 In addition to use in heart failure, the vagomimetic properties of digoxin may be used prophylactically in supraventricular tachyarrhythmias (SVTs), including atrial fibrillation, and for slowing the increase in A conduction caused by quinidine. Also, sulfasalazine patients may have problems with absorption of folic acid and digoxin. Sulfasalazine may even cause severe reaction, such as anaphylaxis, Stevens-Johnson and Lyell’s syndromes, exfoliative dermatitis, eye damage, pleuritis, pericarditis, myocarditis, interstitial lung disease, different liver problems and rhabdomyolysis. This medication might cause rash, urticaria, itching and change of skin color, and rarely lichen planus or toxic epidermal necrolysis. It also affects the kidneys, and might cause oliguria, anuria, toxic nephrosis, nephritis, and nephritic and hemolytic uremic syndromes. This condition requires stopping of the therapy, and it usually gets better for a week or two.
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