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Desyrel is an antidepressant drug that’s prescribed to treat the symptoms of depression.
Desyrel is in a class of medications called serotonin modulators, which work by moderating levels of serotonin (a neurotransmitter ) in the brain.
The Food and Drug Administration (FDA) first approved trazodone in 1981 under the brand name Desyrel.
Desyrel is now available as a generic drug, and multiple drug companies produce it.
The only brand name remaining for this drug is Oleptro.
Besides treating depression, doctors may also prescribe trazodone to treat anxiety, schizophrenia, or uncontrolled movements that occur as a side effect of other medications.
Desyrel for Insomnia Your doctor may prescribe trazodone to treat insomnia or other sleep disorders.
A study in the American Journal of Geriatric Psychiatry in 2014 found the drug to be very effective in treating sleep disturbances in people with Alzheimer’s disease.
Desyrel improved nighttime sleep but did not affect thinking or brain function.
Taking the drug did not lead to daytime sleepiness or naps.
Desyrel Warnings The FDA requires a black-box warning on trazodone, noting that taking the drug could increase the chance of becoming suicidal.
The risk of suicide is greatest when starting treatment or when increasing or decreasing the dose of trazodone.
Suicide risk may be higher for people younger than 24.
Depression may become worse before it gets better when someone starts taking trazodone.
Your doctor will watch you carefully for symptoms of aggression, irritability, panic attacks, extreme worry, restlessness, acting without thinking, abnormal excitement, or any thoughts of suicide when you start the drug.
You should also let friends and family members know if you have these symptoms or worsening symptoms of depression.
Results indicated that SPQ scores of trazodone and gabapentin users did not differ at baseline, and that users of each drug exhibited significant SPQ score improvements at follow-up versus baseline.
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