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Primidone is the generic form of the brand-name drug Mysoline, which is used to treat and prevent seizures.
The medicine can be used alone or combined with other treatments.
It’s also used to treat essential tremor and other neurological conditions.
Primidone is in a class of drugs known as anticonvulsants.
It works by reducing abnormal electrical activity in the brain.
The Food and Drug Administration (FDA) first approved primidone in 1954.
It’s marketed as Mysoline by Valeant Pharmaceuticals, and as generic primidone by several drug manufacturers.
Primidone Warnings Some people may have suicidal thoughts or changes in mental health while taking anticonvulsants such as primidone.
Tell your doctor right away if you experience any of the following symptoms: Panic attack Anxiety Agitation or restlessness New or worsening irritability Depression Acting on dangerous impulses Difficulty sleeping Aggressive, angry, or violent behaviors Abnormally excited mood Suicidal thoughts or actions Preoccupation with death Withdrawing from family and friends Other unusual changes in mood or behavior Before taking primidone, tell your doctor if you have or have ever had: Porphyria (a blood disease) Allergies to any medications A history of mental health disorders or substance abuse Liver disease Lung or breathing problems Also, be sure to tell your doctor if you’re taking sodium oxybate (Xyrem) or the recreational drug GHB before starting primidone.
Tell your doctor that you take primidone before any type of surgery, including dental procedures.
It might take several weeks before you feel the full benefits of primidone.
Don’t stop taking the medicine without first talking to your doctor.
Your seizures may become worse and you may experience unpleasant withdrawal symptoms if you stop taking primidone suddenly.
Be sure to keep all appointments with your doctor and laboratory while taking this medicine.
Pregnancy and Primidone Primidone may harm an unborn baby.
Don’t take this medicine if you’re pregnant or plan to become pregnant.
You should also know that hormonal birth control pills may not work as well if you’re taking primidone.
Talk to your doctor about other birth control options.
The drug is found in breast milk and may hurt a breastfeeding baby.
Don’t breastfeed while taking primidone.
BasicDescription Back to Top Primidone Side Effects Common Side Effects of Primidone Tell your doctor if any of the following side effects are severe or don’t go away: Dizziness Tiredness Difficulty coordinating movements Nausea or vomiting Loss of appetite Serious Side Effects of Primidone Tell your doctor right away if you experience any of the symptoms listed in the Primidone Warnings section above, or any of the following serious side effects: New or worsening seizures Double vision or unusual eye movements Decrease in sexual ability Severe tiredness or weakness Signs of an allergic reaction, which may include rash, hives, itching, difficulty breathing, or swelling of the mouth, face, lips, or tongue Back to Top Primidone Interactions Tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you’re taking, especially those listed in the Primidone Warnings section above, and any of the following: Anticoagulants (blood thinners) such as warfarin ( Coumadin, Jantoven) Antidepressants Disulfiram ( Antabuse ) Doxycycline (Vibramycin) Griseofulvin (Grifulvin) Medications for anxiety, mental illness, or pain Other medications for seizures such as oxcarbazepine ( Trileptal ), phenobarbital, phenytoin ( Dilantin ), and valproic acid (Depakene, Depakote ) Oral contraceptives (birth control pills) Oral steroids such as dexamethasone ( Decadron, Dexone) and prednisone (Deltasone) Sedatives Sleeping pills Tranquilizers Primidone and Other Interactions Primidone may make you drowsy.
Don’t drive a car or operate machinery until you know how this medicine affects you.
Primidone and Alcohol Drinking alcohol may worsen certain side effects of primidone.
Talk to your doctor about this potential interaction.
Back to Top Primidone Dosage Primidone comes as a tablet to take by mouth.
It’s typically taken three to four times daily.
Try to take this medicine around the same time each day.
You can take it with or without food.
Follow the instructions on your prescription label carefully.
Don’t take more or less primidone than is prescribed.
Your doctor will likely start you on a low dose of the drug and gradually increase it.
Primidone Overdose Symptoms of an overdose may include: Confusion Trouble breathing Uncontrolled eye movements If you suspect an overdose, contact a poison control center or emergency room immediately.
You can get in touch with a poison control center at (800) 222-1222.
Missed Dose of Primidone If you miss a dose of primidone, take it as soon as you remember.
However, if it’s almost time for you next dose, skip the missed dose and continue on your regular dosing schedule.
Don’t double up on doses to make up for a missed one.
Back to Top Primidone Pictures Primidone 50 mg-LAN, white, round, Primidone 50 mg-AMN, white, round, Mysoline 50 mg, white, square, Primidone 250 mg-GLO, white, square, Primidone 250 mg-MUT, yellow, round, Primidone 50 mg-GLO, white, square, Primidone 250 mg-SCH, white, round, Primidone 250 mg-AMN, white, round, Mysoline 50 mg, white, square, Primidone 250 mg-WAT, white, round, Primidone 50 mg-MUT, white, round,
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