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Additional information about the drug Pentasa


Pentasa
Pentasa is a prescription medication used to treat ulcerative colitis, or inflammation of the lining of the colon. It helps relieve the symptoms of ulcerative colitis including diarrhea, rectal bleeding, and stomach pain. Pentasa belongs to a group of drugs called aminosalicylates. These work by stopping the body from producing a certain substance that may cause pain or inflammation in the colon.
Common side effects of mesalamine include headache, gas, and stomach pain.
Pentasa is a prescription medication used to treat ulcerative colitis (UC). UC is a condition in which part or all of the lining of the colon (also known as the large intestine) is swollen or worn away. It is used to cause the disease to temporarily go away (“induce remission”) and to keep it from coming back (“maintain remission”).
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Pentasa is a prescription medication used to treat ulcerative colitis (UC). UC is a condition in which part or all of the lining of the colon is swollen or worn away. It also works inside your rectum (lower intestine) to help reduce bleeding, mucous and bloody diarrhea caused by inflammation (swelling and soreness) of the rectal area.
Pentasa may be found in some form under the following brand names:
Pentasa is part of the drug class:
Serious side effects have been reported with mesalamine. See “Pentasa Precautions” section.
Common side effects of mesalamine include:
Other less common side effects include:
This is not a complete list of mesalamine side effects. Ask your doctor or pharmacist for more information.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
This is not a complete list of mesalamine drug interactions.  Ask your doctor or pharmacist for more information.
Serious side effects have been reported with mesalamine including:
Increasing fecal butyrate in ulcerative colitis patients by diet: controlled pilot study.Randomized clinical trial of Plantago ovata seeds (dietary fiber) as compared with mesalamine in maintaining remission in ulcerative colitis.

  • Aminosalicylates, including sulfasalazine and mesalamine delivery systems, are most commonly associated with sulfa-related effects (sulfasalazine) or intolerance, with rare instances of nephritis, pulmonitis, hepatitis, or worsening colitis.
  • In all four studies, healthy adults received placebo once daily or MMX mesalamine 4.8 g once daily on days 1-4 in one of two treatment sequences.
  • Pyloric stenosis or other organic or functional obstruction in the upper gastrointestinal tract may cause prolonged gastric retention of mesalamine which would delay mesalamine release in the colon.
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