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Plavix is a prescription medication used to prevent blood clots in people who have recently been hospitalized with chest pain, or for people who have recently had a heart attack or stroke. Plavix belongs to a group of drugs called antiplatelets, which help prevent harmful blood clots from forming in the body.
This medication comes in tablet form and is taken once a day, with or without food.
Common side effects of clopidogrel include bleeding, headache, dizziness, and nausea.
Plavix gets converted to its active form by an enzyme in the body known as CYP2C19. Drugs such as clopidogrel that require activation by the body are known as prodrugs. Some patients have a deficiency in CYP2C19. Patients with a deficiency in CYP2C19 are known as “poor metabolizers” or “intermediate metabolizers.”
CYP2C19 testing is done to determine whether clopidogrel is likely to be an effective treatment. Many factors can affect levels of clopidogrel in the blood, such as drug interactions. Without testing, clopidogrel may not be an effective treatment. If you are a poor or intermediate metabolizer, your doctor may adjust your dose of clopidogrel.
Without being activated, clopidogrel is not able to stop blood clots from forming. In poor or intermediate metabolizers, clopidogrel may not get converted to its active form, and may not be effective at preventing blood clots. Being a poor or intermediate metabolizer is associated with a higher risk of heart attack or stroke in patients being treated with clopidogrel.
Plavix is a prescription medication used to prevent blood clots in people who have recently been hospitalized with chest pains, or for people who have recently had a heart attack or stroke. It is also used in people with certain heart and blood vessel disorders.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Plavix may be found in some form under the following brand names:
Plavix is part of the drug class:
Plavix can cause serious side effects including:
Tell your doctor if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of clopidogrel. For more information, ask your doctor or pharmacist.
Tell your doctor about all the medicines you take, including prescription, non-prescription medicines, vitamins and herbal supplements.
Plavix may affect the way other medicines work, and other medicines may affect how clopidogrel works.
This diagnosis should be considered if clinical symptoms consistent with cyanocobalamin deficiency are observed. The total content of sodium in each capsule is 304 mg. Long-term administration of bicarbonate with calcium or milk can cause milk-alkali syndrome. Inhibition of platelet aggregation by clopidogrel is entirely due to an active metabolite.
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