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Additional information about the drug Diflucan


Diflucan, sold under the brand name Diflucan, is a medication used to treat fungal infections like thrush in the mouth and throat and yeast infections in women.
Diflucan belongs to group of drugs known as antifungals, which work by preventing fungus from making its own form of plant-based cholesterol that the fungus needs to survive.
Diflucan was approved by the Food and Drug Administration (FDA) under the brand name Diflucan in 1990, and is manufactured by Pfizer.
Diflucan Warnings If you are allergic to fluconazole or any of its inactive ingredients, you should not take fluconazole.
If you are taking medications that can change the electrical activity in the heart you should not take this drug.
Also, if you have severe kidney problems (kidneys with a creatinine clearance, CrCl, or urine output 50 ml/ minute or less), your body may not be able to eliminate fluconazole as quickly as it should.
Your doctor may need to find a special dose that works best for you.
Be sure to let your doctor know that you have kidney problems before taking this medication.
People who are on dialysis should receive the full dose of fluconazole after they have finished their dialysis procedure.
Talk to your doctor before taking fluconazole if you: Are taking medications that change heart rhythm or conduction like Ery-tab ( erythromycin ), Orap (pimozide), or quinidine Have kidney problems Are pregnant Additionally, if you are allergic to azoles (the building block of a certain class of antifungal drugs that includes fluconazole), you should not take fluconazole.
It should also be noted that people with certain sensitivities must be careful with various dosage forms of fluconazole.
For example, people who may have inherited certain genetic conditions, including intolerances to certain sugars, such as glucose-galactose, lapp lactase, or sucrose, should avoid Diflucan capsules because they contain lactose.
People with glycerol sensitivities should avoid fluconazole syrups because the glycerol may cause unpleasant symptoms like diarrhea, stomach discomfort, or headaches.
Pregnancy and Diflucan In general, it’s not recommended that pregnant women take this medication.
Diflucan can harm the fetus and should only be taken in situations when there are no other safer options available.
Regardless, you should tell your doctor if you are pregnant or plan to become pregnant before taking this medication.
Diflucan (or azole) resistance is predominantly the consequence of previous exposure to fluconazole (or other azoles), particularly repeated and long-term exposure ( 338-340 ).

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